You can't run e85 in anything not made to run e85. Just can't do it. You need stainless steel lines and tank, ethanol is extremely corosive(so don't splash any on your paint if you car/truck can use it ). You also need an ECU that can recognize what type of fuel you are using and adjust things like timing, spark, and fuel pulses among other things.

 

And even if you do have a FlexFuel vehicle, it was really designed to run on gas. All you end up doing is throwing a bunch more fuel at it when running E85 since it doesn't have the BTU content that gasoline does...you have a big drop in miles per gallon. My manual for my 2007 Dodge Ram says to expect a 20% reduction in mileage; of course I can't test it out since E85 is not available where I live (even if it was I wouldn't run it at the current prices).

Now if your engine was really designed to run on E85 it would be a different story, but that is not the case...

 

n-butanol, which can be a biofuel instead of being petroleum derived as it is today, can replace gasoline on a one for one basis. Butanol has nearly the same BTU content per volume/mass as gasoline, and burns much more completely in ICEs. Therefore, there may be negligible power and mileage gains or losses when switching from gasoline to butanol.

Emissions of engines burning butanol are far below those of gasoline. Butanol is not corrosive like ethanol is, and is much safer as a liquid fuel than either gasoline or ethanol from a vapor pressure/flash point perspective. There are no special fuel system requirements necessary when switching from gasoline to butanol like there would be when using ethanol. Existing ethanol production facilities can be converted to produce butanol instead.

Bio-sources for butanol production can be everything from yard waste, any cellulosic trash, industrial organic wastes (such as whey waste from cheese factories), algae, etc. There is enough waste and other sources in the US today to replace all of our gasoline.

Butanol is as near a perfect liquid fuel replacement for gasoline used in ICEs as we are ever likely to find. Until the world switches to fuel cells for power, butanol is the only viable alternative.

Butanol can also be shipped through the existing gasoline pipeline infrastructure. Ethanol cannot, and has to be shipped by rail or truck because of its corrosive nature and affinity for water. Pipeline is a much more efficient way to ship fuel.

For more information, see http://www.butanol.com

http://en.wikipedia.org/wiki/Butanol